A single carbon atom stitches flat molecules into 3D structures

Image: Phys.org
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- When drugmakers want to improve on compounds they have already created, they can replace a carbon atom with a nitrogen atom. While effective, the techniques they use to perform this chemical swap, known as skeletal editing, have some downsides. For example, older approaches often require harsh…
- Flat is fine for a sheet of paper, but many of the most useful molecules need depth. Now, researchers from Japan have found a way to give them that depth using nothing more than a single carbon atom.