Natural RNA modifications in archaea mirror those used in medicine

Image: Phys.org
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- An international research team led by TU Darmstadt Professor Beatrix Süß, working in close collaboration with partners in Germany and Denmark, has elucidated how an RNA switch newly developed at TU Darmstadt recognizes the antibiotic doxycycline and thereby selectively activates or deactivates…
- RNA therapeutics open up new possibilities for the targeted and precise treatment of diseases. To ensure that RNA molecules remain stable in the body and can reliably exert their effects, they undergo specific chemical modifications. However, such modifications to the RNA backbone also occur…