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Science

Genome accessibility reveals disease risk that gene expression misses

Image: Nature

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Wires & papers of record

  • Nature · October 7, 2026 00:00
    Nature, Published online: 07 October 2026; doi:10.1038/d41586-026-03072-5 Most disease-associated genetic alterations do not affect the genes themselves, but instead change how strongly they are expressed, often by modifying genome accessibility. Gene expression and accessibility have now been…