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Science

Late-life semaglutide treatment slows ageing and extends lifespan in female mice

Image: Nature

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Wires & papers of record

  • Nature · September 2, 2026 00:00
    Nature, Published online: 02 September 2026; doi:10.1038/s41586-026-10940-7 Semaglutide treatment for 3 months in female mice improved physiological function, attenuated hallmarks of ageing and modulated nutrient sensors and conserved genetic regulators of ageing.
  • Nature · September 2, 2026 00:00
    Nature, Published online: 02 September 2026; doi:10.1038/d41586-026-02468-7 In one inbred strain of laboratory mice, late-life treatment with a GLP-1 drug extends lifespan. This effect might be more than just a consequence of calorie restriction.
  • Nature · September 2, 2026 00:00
    Nature, Published online: 02 September 2026; doi:10.1038/d41586-026-02757-1 Older female mice given an anti-obesity medication lived longer and in better health than did mice not taking one.