PLA2G2D in tumour-draining lymph nodes regulates anti-tumour immunity

September 9, 2026 · 12:00 am 2 sources

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• PLA2G2D in tumour-draining lymph nodes regulates anti-tumour immunity
  Nature · September 9, 2026 00:00
  Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-10954-1 A specific population of macrophages that express high levels of the enzyme PLA2G2D in tumour-draining lymph nodes is associated with poor prognosis in patients, and inhibiting PLA2G2D improves anti-tumour immunity in…
• Proximity-guided graph learning reveals tumour-associated proximity antigens
  Nature · September 9, 2026 00:00
  Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-11003-7 A proximity-mapping atlas defines tumour-associated proximity antigens, revealing disease-associated membrane spatial communities, and identifies EGFR–CDCP1 as a co-target pair that enhances tumour killing by multispecific…