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‘Self-blinking dyes’ simplify nanoscale imaging without sacrificing precision

Image: Phys.org

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  • Phys.org · October 7, 2026 21:30
    Nanobodies are extremely small antibody fragments that bind to specific molecules. When nanobodies are labeled with dyes, they can be used as probes to enhance super-resolution microscopy. However, conventional blinking dyes often perform poorly when attached to nanobodies, limiting their…