Super-resolution imaging reveals that cohesin prevents local mixing of compact, active genome domains
Image: Phys.org
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- The human genome is about two meters (6.6 feet) long, yet it is folded inside a cell nucleus only about 10 micrometers in diameter. To fit into this tiny space, DNA is wrapped around histone proteins to form nucleosomes, which are further organized into chromatin. For decades, chromatin has often…