An operational perturbation proteomics-based virtual cell model

September 7, 2026 · 12:00 am 2 sources

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Wires & papers of record

• The secret life of a cell-cycle gatekeeper of breast cancer
  Nature · September 7, 2026 00:00
  Nature, Published online: 07 September 2026; doi:10.1038/d41586-026-02470-z A newly discovered function for the protein Rb explains why inhibiting cell division can enhance the signalling mediated by the oestrogen receptor that drives breast cancer.
• An operational perturbation proteomics-based virtual cell model
  Nature · September 9, 2026 00:00
  Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-11001-9 Temporal protein-abundance measurements from systematically perturbed breast cancer cell lines were generated to develop ProteinTalks, a virtual cell model that functions as an operational tool for diverse drug discovery…